Alcohol Is Not More Dangerous than Drugs!

          It is absurd to conclude that alcohol is more dangerous than heroin and crack cocaine as headlines around the world proclaimed last week.  In a study published in the respected British medical journal, Lancet, Dr. David Nutt at the University of Bristol stated exactly that after evaluating twenty drugs for their potential for physical harm, addictiveness, and effects on society.  What was not widely reported was that the study concluded that heroin, crack cocaine and crystal meth were the deadliest to the individual user, but that alcohol was considered more damaging because of its greater social effects, mainly because it was more widely used.  This is a little like saying that driving a car is more deadly than skydiving, because more people drive a car.  It is interesting to note that when Britain increased the penalties for marijuana use last year, Dr. Nutt voiced his opposition for which he was fired as the UK’s Chief Drug Advisor.

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Meningitis

           Meningitis can be a catastrophic illness with devastating consequences, often including death and it can occur at any age from infants to seniors.  Viruses and bacteria are responsible for most cases of meningitis, but less common infectious agents such as fungi can also play a role.  Meningitis occurs when these infectious agents gain access to the cerebrospinal fluid surrounding the brain and spinal cord.  Viral meningitis, sometimes called aseptic meningitis, can present with symptoms similar to bacterial meningitis.  While more common, it is generally less serious than bacterial meningitis and patients usually get better without specific treatment.  Most cases of viral meningitis occur in children under the age of five.  Recently, West Nile Virus has been identified as an important cause of viral meningitis.  The common factor in all forms of meningitis is inflammation and swelling of the membranes covering the brain and spinal cord. 

Incidence: 

          For the purposes of this discussion we will focus on bacterial meningitis and the three bacteria mainly responsible for this more serious form of the disease, Streptococcus pneumoniae, Hemophilus influenzae type b and Neisseria meningitidis.  These are the most common causes of bacterial meningitis beyond the neonatal period.  A vaccine is now available for each of these three bacteria, and their widespread use has significantly decreased the incidence of these devastating infections.  Meningitis cause by Hemophilus influenzae type b was the leading cause of meningitis in children before the 1990s when the Hib vaccine became available.  In a testament to the importance of vaccines in preventive medicine, it is now the least common cause.  Meningitis caused by Streptococcus pneumoniae is now the most common cause of bacterial meningitis in infants, children and adults in the United States, followed by Neisseria meningitidis. 

Transmission:   

          The infectious agents causing meningitis are spread by respiratory contact, although they are less contagious than infections such as the common cold.    Spread is usually by exchange of respiratory and throat secretions, such as by coughing and kissing.  They are not spread by casual contact or by merely breathing the air where a patient has been.  The bacteria causing meningitis generally reach the cerebrospinal fluid surrounding the brain and spinal cord by spread from the bloodstream. 

Signs and Symptoms:   

          It is important to understand that the presenting symptoms and the most likely cause of meningitis can vary from one age group to another.  Symptoms can appear quickly or after several days, but typically within 3 to 7 days after exposure.  The symptoms of meningitis include fever and chills, nausea and vomiting, mental status changes, headache, stiff neck and sensitivity to light.  In infants and young children, the symptoms can be much more subtle and a high index of suspicion is necessary.  Because bacterial meningitis is a true medical emergency, anyone with these symptoms should seek immediate medical attention.  

Diagnosis and Treatment: 

          The only way to confirm a diagnosis of meningitis is to do a lumbar puncture in order to examine the cerebrospinal fluid.  When treated in time, each of the three most common bacteria causing meningitis can be treated with antibiotics.  Because the disease can progress rapidly, physicians may begin intravenous antibiotics before the specific bacterial cause has been identified in the cerebrospinal fluid.  Corticosteroids are often used to suppress inflammation and reduce swelling and pressure in the brain. 

Neisseria Meningitidis: 

          It is no wonder that meningitis caused by the bacterium Neisseria meningitidis is one of the most dreaded infections by both health care providers and patients, alike.  For that reason and because vaccination recommendations for this form of meningitis have recently been changed, it has been singled out for special attention in this article.  Neisseria menigitidis occasionally presents as a fulminant infection with the rapid appearance of a rash consisting of red and purple spots mainly on the trunk and lower extremities.  This overwhelming invasion of the bloodstream is referred to as meningococcemia and without immediate treatment with penicillin it can lead to loss of limbs, brain damage or death.  

Meningococcal Vaccine Recommendations: 

          The CDC has recently made a change in the recommendations for the meningococcal vaccine to prevent infection with Neisseria meningitidis.  While it still recommends the first dose be given at age 11, it now recommends an additional booster at age 16, because immunity wanes after five years.  If the first dose was not given until age 13-15, then the booster should be given five years later.  Conditions such as crowding and fatigue increase the likelihood of spreading respiratory infections and thus put young adults at a higher risk of acquiring meningococcal meningitis.  At risk groups include military recruits and college freshman living in dorms.  Travelers to areas where meningitis is endemic should consult with their personal physician concerning whether they should receive the meningitis vaccine. 

          For more information about the vaccine recommendations visit the following website:       http://www.cdc.gov/meningitis/about/prevention.html

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The Perils of Pot

Marijuana is Harmful to Your Health

          Marijuana is now the most commonly used illicit drug in the United States.  Donald Hagler, MD of the American College of Pediatricians points out that use of marijuana is associated with lower educational accomplishment, lower work productivity, and increased risk for motor vehicle accidents, in addition to heart and lung disease.  The main active ingredient in marijuana is the mind altering chemical delta-9-tetrahydrocannol or THC.  THC affects nerve cells and may lead to premature age related loss of nerve cells.  Marijuana impairs judgment, coordination, balance, ability to pay attention and reaction time.  Hagler goes on to point out that students who use marijuana regularly have lower test scores and grades and are less likely to achieve personal goals.

          Smoking marijuana is more harmful than tobacco, because it contains 50 to 70% more carcinogens.  It has the same effect as tobacco on the respiratory system, causing chronic cough, respiratory infections, bronchitis, emphysema and lung cancer.  Furthermore, it increases blood pressure and heart rate and decreases the oxygen carrying capacity of the blood.  Experts say that the marijuana of today is 3 to 5 times more potent than what was available in the 1960s.  It is considered a gateway drug to even more dangerous drugs like cocaine and long term use can lead to addiction.

          For all these reasons, making marijuana more available is not a good idea.  Many states and the federal government have spent millions of dollars in advertising campaigns to reduce the use of tobacco.  If marijuana is worse, why would we want to legalize it?  It is a no-brainer that legalization would lead to an increase in marijuana use, an increase in medically related expenses and increased availability of the drug to children.

          It is a little known fact that during prohibition (1920 to 1933), there was a significant decrease in alcohol use.  It takes as little as eight to ten years of heavy drinking to develop cirrhosis of the liver.  Public Health statistics show that in the years following prohibition corresponding to that timeframe the incidence of cirrhosis decreased, only to increase again after it was repealed.  So why, then, did alcohol use decrease during prohibition?  Because alcohol was harder to get, but even more importantly, because the majority of Americans are law abiding citizens!  If something is against the law, they don’t do it.  No one is suggesting that we return to prohibition.  But the real lesson we learned is that once the cat is out of the bag, there is no going back.  Why, then, open Pandora’s box by legalizing marijuana now.  For the sake of our children we should oppose any efforts to legalize marijuana or any other illicit drugs.

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Lamenting the Demise of the Physical Examination

Lamenting the Demise of the Physical Examination

          It was in a top tier medical center, that I recently found myself in the unfamiliar role of the patient rather than the doctor.  Somehow the dynamics seemed different than they had during all the years that I had orchestrated this same scenario.  Thankfully, I only need to visit the doctor once in the while and then only for routine matters.  But this time, and I have noticed it increasingly since then, there was a change.  I sat fully clothed on the exam table while the doctor sat with his back to me staring into a computer.  He read from a standard set of questions and each of my brief answers brought on a short burst of typing until the next question.  With the questions over, my doctor turned toward me and really looked at me for the first time.  After a cursory glance, he listened through my shirt with his stethoscope to maybe one breath from each of my lungs and then he placed it somewhere in the vicinity of my heart for what couldn’t have been more than a few beats.  “Everything looks fine”, he exclaimed.

          To say that there has been a revolution in medicine since I was trained would be an understatement.  The advent of sophisticated imaging devices in particular has changed the way medicine is practiced and has been a life-saver for many patients.  But it has come with a price, both literally and figuratively.  Not only have health care costs skyrocketed, but patients have also paid in other ways.  Recently trained doctors rely more on testing and less on physical examination to make a diagnosis than we did in ‘the old days’.  Back then, the ‘laying on of hands’ not only cemented the doctor patient relationship, but it also provided a sense of reassurance to the patient…reassurance that the doctor had really given you a good check up and reassurance that your doctor really cared about you as a person.

          Along with all the other courses first year medical students took when I went to medical school, we spent the entire year dissecting cadavers.  In many medical schools today gross anatomy is either optional or nonexistent.  I must confess that this aptly named course was my least favorite, but by actually seeing all the parts of the body up close and personal we really did learn anatomy. During the second year of medical school we began to apply what we had learned in anatomy and it became quite apparent how it related to the physical exam.  We had a course called ‘Physical Diagnosis”, which we affectionately referred to as P-Dog, using a small maroon textbook titled “Bedside Diagnostic Examination”, by DeGowen & DeGowen.  This now classic manual was compact enough that we could carry it with us on our rounds.  That year we also got black bags loaded with the tricks of the trade and donned our short white coats in preparation for our first physical exam.  To this day, I still remember going into the hospital room with one of my classmates to meet our very first patient and awkwardly asking all the questions in the history and review of systems that we had practiced.  And I will never forget this kind older gentleman who let us poke and prod him, all the while probably thinking he had been visited by Doogie Howser.

          The physical examination was constantly stressed by our professors in medical school and we learned much from watching them perform the exam.  To me neurologists have always been the masters of the physical exam.  Back then they could easily be distinguished from other physicians by the extra large percussion hammers with a wheel on the end that they all seemed to have…so large, in fact,  that it often extended out through the top of their black bags.  Alas, one hardly ever sees a doctor carrying a black bag any more.

          Later in my training, I remember examining a woman who was being admitted to the hospital.  It wasn’t unusual for each medical student or intern to get 20 admissions in one night back then, and even working around the clock, it was difficult to get everything done.  The following morning I presented her case to the senior resident while he scrutinized my write up.  When I was finished, he asked if I had examined her cervical lymph nodes…a question for which he already knew the answer.  As a novice, I had skipped something that I thought was unrelated to her reason for admission.  When I confessed that I had not examined her cervical lymph nodes, he asked in a mild but, for me, withering tone, “You didn’t think it was important?”  I had no answer.  That was a good lesson and I have never forgotten it or the resident who set me straight that morning.  Since then, no matter how busy I have been, I have always tried to remember the importance of a thorough physical examination.

          I know.  Things are different now.  Every year the body of information that physicians must learn grows exponentially.  Of necessity, medicine must be practiced differently, but I am encouraged to see that there is a small, but growing renewed emphasis on the importance of the physical examination at some medical schools.  And I must say, that I am constantly impressed with the young physicians I encounter who are being trained in our medical schools these days.  Finally, I am happy to report that I am adjusting to the new dynamic and my doctor and I are getting on just fine.  We truly do have the greatest health care system in the world!

Are They Obsolete?
Are They Obsolete?

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Walking and Weight

          The results of an interesting study which appeared in the October issue of Medicine and Science in Sports and Exercise were reported in USA Today by Janice Lloyd.  The number of steps per day taken by adults from four countries was measured using pedometers and the results show an interesting correlation with obesity rates: 

United States:                   2.5 miles/day                   34% obesity rate

Japan:                              3.5 miles/day                    3%  obesity rate

Switzerland:                      4.8 miles/day                     8%  obesity rate

Australia:                          4.8 miles/day                   16%  obesity rate 

          Clearly, American adults walk less than adults in other countries and have a significantly higher obesity rate.  Walking less than 2.5 miles per day is considered sedentary.  A lack of activity is also associated with hypertension, heart disease, diabetes, some types of cancer and other chronic illnesses.  The take home lesson here is that activity is an important adjunct to decreasing intake of calories to maintain proper weight and walking is a good way to increase activity.  

To read the entire article, follow the link below. 

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